GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs11976180 | 1 | rs1320894 | chr7:143751802 | ARHGEF35 | chr7:143883677-143892736:- | -0.34 | -5.98 | 5.07E-9 | Obesity-related traits |
| BLCA | cis | rs1474698 | 1 | rs1320996 | chr6:56100431 | COL21A1 | chr6:55921389-56258892:- | 0.36 | 6.56 | 1.79E-10 | Pulse pressure |
| BLCA | cis | rs1577917 | 1 | rs13217384 | chr6:86720000 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.17 | 3.03E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs9475752 | 1 | rs13220510 | chr6:56779141 | BEND6 | chr6:56819773-56892138:+ | -0.31 | -4.31 | 2.05E-5 | Menarche (age at onset) |
| BLCA | cis | rs2243480 | 1 | rs13220979 | chr7:65363204 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.38 | 1.53E-5 | Diabetic kidney disease |
| BLCA | cis | rs11976180 | 1 | rs13226728 | chr7:143746578 | ARHGEF35 | chr7:143883677-143892736:- | -0.33 | -5.84 | 1.11E-8 | Obesity-related traits |
| BLCA | cis | rs2243480 | 1 | rs13235972 | chr7:65883605 | CCT6P1 | chr7:65216092-65228661:+ | 0.37 | 4.98 | 9.6E-7 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs13237037 | chr7:65997882 | CCT6P1 | chr7:65216092-65228661:+ | 0.37 | 4.89 | 1.48E-6 | Diabetic kidney disease |
| BLCA | cis | rs11976180 | 1 | rs13243677 | chr7:143746572 | ARHGEF35 | chr7:143883677-143892736:- | -0.34 | -5.92 | 7.23E-9 | Obesity-related traits |
| BLCA | cis | rs2243480 | 1 | rs13247184 | chr7:65358928 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.45 | 1.11E-5 | Diabetic kidney disease |
| BLCA | cis | rs7017914 | 1 | rs13252719 | chr8:71734569 | XKR9 | chr8:71581600-71648176:+ | 0.82 | 17.79 | 5.09E-52 | Bone mineral density |
| BLCA | cis | rs7017914 | 1 | rs13253842 | chr8:71625503 | XKR9 | chr8:71581600-71648176:+ | 0.82 | 17.69 | 1.34E-51 | Bone mineral density |
| BLCA | cis | rs13256369 | 1 | rs13282915 | chr8:8570891 | CLDN23 | chr8:8559666-8561616:+ | -0.23 | -4.01 | 7.24E-5 | Obesity-related traits |
| BLCA | cis | rs2243480 | 1 | rs13310597 | chr7:65598540 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.59 | 5.95E-6 | Diabetic kidney disease |
| BLCA | cis | rs10935120 | 1 | rs13322305 | chr3:134310791 | ANAPC13 | chr3:134196547-134204865:- | 0.48 | 7.6 | 2.33E-13 | Height |